Clinician-Guided Tapering

Antidepressants don’t have to be forever

Outro Health pairs you with a clinician to build an evidence-based tapering plan, so you can safely reduce your medication with support every step of the way.

A virtual clinic, that helps people safely taper off antidepressants

Our healthcare system is great at starting medications, and terrible at stopping them. Outro Health clinicians are trained to support you in safely reducing your reliance on medications—and discovering a fulfilling life beyond them.

Hyperbolic tapering plans
Clinicians trained in deprescribing
Holistic non-drug support

Tapering that’s based on science, and personalized to you

8/10 patients tried to get off their antidepressant before finding Outro

7x: hyperbolic tapering has a much higher success rate than standard protocols

93% of patients trust Outro clinicians more than their previous prescriber

95% of patients had a better experience tapering with Outro

Clinician drawing a hyperbolic tapering curve of antidepressant dose over time
Dr. Mark Horowitz

World-leading experts in safe deprescribing

If your last taper attempts didn't work, it probably wasn't your fault. 9/10 long-term antidepressant users experience withdrawal symptoms, which make stopping difficult. We use the first science-based method to limit withdrawal symptoms.

How it Works

Feel seen from your first visit

You don’t need to be “ready” or have it all figured out to start. Our intake and 45-minute evaluation are built to hear your full story—including past tapers, fears, and goals—so your clinician can map a path that will help you succeed.

Step 1

Tell us your story

Share your medication history, what you've tried before, and what you're hoping for now.

Illustration of a journal mapping a tapering path from a pill bottle to a growing sprout
Step 2

Discuss your options

Book an evaluation, and meet your clinician to map out what Outro Health could look like for you.

Illustration of a clinician and patient discussing a personalized tapering plan
Step 3

Start your taper plan

Start tapering with ongoing monitoring, dose adjustments, and clinical support.

Illustration of a step-by-step antidepressant tapering path leading to a finish flag
Deprescribing Experts

Clinicians that understand tapering & withdrawal

The relationship matters. Our clinicians are trained in deprescribing, understand withdrawal, and listen to you and your symptoms throughout the tapering journey.

A long-term relationship
Trained in deprescribing
Symptoms guide the plan
Compounded Rx delivery

Kristen Massingill

Psychiatric Nurse Practitioner

After years of watching patients hit roadblocks trying to deprescribe, I realized how little infrastructure existed for people who were motivated and ready to explore life beyond medication. Patient education has always been central to my practice, and I believe people deserve to understand their options fully, not just the path onto medication.

Practicing for 15+ years

Kristin Hicks

Psychiatrist

I didn't fully grasp antidepressant withdrawal until experiencing it myself in 2021. When a friend shared Mark's article, I reached out not expecting a response—but he replied, we stayed connected, and I joined Outro Health as a clinician in 2024. This experience transformed my practice toward holistic care and non-drug interventions.

Practicing for 10+ years

It’s not you, antidepressant withdrawal is common

2/3

of Americans on antidepressants have been taking them long term.

10x

Long-term antidepressant users are 10x more likely to experience withdrawal symptoms.

8/10

of long-term antidepressant users struggle to stop, often because of withdrawal.

Lexapro

escitalopram

Zoloft

sertraline

Prozac

fluoxetine

Cymbalta

duloxetine

Effexor

venlafaxine

Pristiq

desvenlafaxine

Celexa

citalopram

Paxil

paroxetine

Desyrel

trazodone

Trintellix

vortioxetine

Remeron

mirtazapine

Others

More Medications

Get holistic support for tapering & beyond

Woman smiling at the Outro Health app after logging a sertraline dose reduction
Personalized tapering plans

A taper plan based on science and personalized to your medication history, present state, and future goals.

Kristen Massingill, psychiatric nurse practitioner at Outro Health, specializing in antidepressant tapering
Clinicians who get deprescribing

Every Outro Health clinician is trained in hyperbolic tapering by world-leading experts, like Dr. Mark Horowitz.

Antidepressant capsule poured from a prescription bottle into an open palm
Access to custom prescriptions

Compounded doses at your door, refill coordination, and between-visit messaging—so you can focus on how you feel.

Outro Health app showing a live peer support group and a tapering and sleep hygiene session
Tools for life beyond medication

Get connected with the community and lifestyle tools that help you through your taper, and prepare you for life after medication.

Real Results

The proof is in the program

Members who tapered safely—and didn’t do it alone.

No one tells you that stopping these drugs is a trip through hell that can damage many aspects of your life. The only way to survive (in my opinion) is with the help of experts and others who have undertaken this journey before you. You will need a guide and someone to hold your hand - Outro is that guide.
Illustrated portrait of Sandi, an Outro Health patient tapering venlafaxine
Sandi

Tapering Venlafaxine

I thought I may be on these meds forever I can at least now see the light at the end of the tunnel and will get to meet myself after all these years and learn what Lily likes.
Illustrated portrait of Lily, an Outro Health patient tapering sertraline
Lily

Tapering Sertraline

Just knowing I'm not alone has been the biggest comfort to me. Outro's clinicians have been nothing short of compassionate and they actually listen closely to you and believe you when you say 'hey, this is what I'm feeling.' I would never do this without this kind of support again.
Illustrated portrait of Kelly, an Outro Health patient tapering venlafaxine
Kelly

Tapering Venlafaxine

When I started researching going off of SSRIs after extended use (I've been on 200mg for 14 years) I was alarmed to learn that withdrawal can be worse than the original symptoms. Having a place like Outro, that specializes in tapering off safely with minimal pain, is such a relief.
Illustrated portrait of Jennifer, an Outro Health patient tapering sertraline
Jennifer

Tapering Sertraline

A way to get hyperbolic tapering help from a real professional. This doesn't exist anywhere and leaves many of us whose minds and bodies have become dependent on these drugs some hope of getting off of them.
Illustrated portrait of James, an Outro Health patient tapering citalopram
James

Tapering Citalopram

I know it's scary, especially after so many years and even decades. But Outro works so closely with you and accommodates your needs while also making sense of it to you. I may be wording this bad but I really mean it when I say Outro has changed my life and what I thought possible for myself.
Illustrated portrait of Brooke, an Outro Health patient tapering fluoxetine
Brooke

Tapering Fluoxetine

FAQs

Explore common questions about safe antidepressant tapering, withdrawal symptoms, lifestyle strategies, and how Outro works.

How does Outro Health help reduce my risk of withdrawal and relapse?

Outro Health provides flexible, medically-supervised tapering plan with gradual dose reductions tailored just for you. Our hyperbolic tapering method, where reductions become progressively smaller, gently minimizes nervous system disruption and withdrawal discomfort. We personalize your tapering plan based on your response, preferences, and what's happening in your life.

How is Outro Health different from working with another provider?

Safe antidepressant deprescribing requires a comprehensive approach that is often difficult for an individual prescriber to provide due to the time required. It also requires up-to-date knowledge on the latest techniques in tapering antidepressants that are not yet widely taught in the United States. Think of Outro Health as a specialist in tapering.

At Outro Health, we walk with you every step of the way. Our specialized, high-touch care team takes time to get to know you and your goals, and provides an advanced, individualized approach to tapering off antidepressants informed by the latest guidance and clinical evidence. Through Outro Health’s app, your symptoms and progress are continuously monitored by your provider, who can reach out to offer coping strategies or adapt your care plan accordingly. If you have questions or concerns that arise in between appointments, your Outro Health provider is available via 1-to-1 chat.

What is hyperbolic tapering?

Hyperbolic tapering (sometimes called the Horowitz-Taylor method) is based on the fact that as antidepressant dose goes up, drug action on brain cells increases, but not in equal steps. Higher dosages have less and less additional influence – a decreasing return on investment. The graph showing this is called a hyperbolic curve (goes up faster at low doses, and flatter at higher doses).

Tapering based on this method gradually reduces the drug following this natural curve, with the size of dose reduction getting smaller as the dosage gets closer to 0mg. These very low doses are difficult to make up with commonly available tablets, so compounded medications become important. To learn more, speak with an Outro Health clinician by scheduling your evaluation.

What if I've tried to stop before?

Many people have difficulties when they try to go off antidepressants. Our team of expertly trained clinicians will develop a tailored tapering program, informed by the latest scientific evidence and designed to minimize withdrawal effects - even for these people who have tried to stop before.

What medications does Outro Health taper?

We currently offer taper management for antidepressant medications. You can see the full list here.

We are making preparations to expand to other psychotropic medications like benzodiazepines and gabapentinoids, which also follow the hyperbolic tapering method. You can express an interest in tapering these medications in our sign-up form.

Where is Outro’s tapering program available?

US map of the 14 states where Outro Health's tapering program is available: Arizona, California, Colorado, Connecticut, Florida, Illinois, Michigan, New Jersey, New York, Oregon, Pennsylvania, Texas, Utah and Washington

You don’t have to taper alone

Start with a clinician-guided plan built around your medication, your symptoms, and your pace.

Two women smiling together over a phone, supporting each other