We believe everyone should have access to safe deprescribing
At Outro Health, we're building the solution that many of our team members wish they'd had when deciding to discontinue their medications. Our dedication stems from a deep appreciation for good science and patient agency.
From severe withdrawal to rewriting national guidelines
Outro Health co-founder Dr. Mark Horowitz was prescribed an antidepressant while in medical school, on his way to earning a PhD in the neurobiology of depression and the pharmacology of antidepressants. Years later, as a training psychiatrist in the UK, Mark followed traditional guidance to wean himself off his antidepressant, only to experience panic attacks, sleep disruptions, and a depression far worse than anything he had experienced before.
Left searching for solutions, Mark found an online community of thousands of others in similar situations. Founded by Adele Framer, an advisor to Outro Health, this community inspired Mark’s research into safely stopping antidepressants and the development of hyperbolic tapering, which the backbone of Outro Health’s individualized tapering plans. In 2024, Dr. Horowitz published the Maudsley Deprescribing Guidelines—the first textbook dedicated outlining neurobiology-based principles and approaches to safely stopping various psychotropic medications.
Having had her own difficulties going off an antidepressant, Adele has dedicated more than a decade to being a lay researcher in and patient advocate for safe tapering, counselling more than 10,000 people through their journeys off medication. We draw on Mark and Adele’s world-leading knowledge to support our team in providing the highest level of care and safety to our members.
Fast forward to today, hyperbolic tapering is now endorsed by national authorities in the United Kingdom and, in 2024, Dr. Horowitz published the Maudsley Deprescribing Guidelines—the first textbook dedicated outlining neurobiology-based principles and approaches to safely stopping various psychotropic medications.
"I was on antidepressants for 15 years and when I tried to come off them, at the end of my Ph.D., I struggled with severe withdrawal symptoms. It was the most awful experience of my life. I found there was a lack of support and knowledge from clinicians and researchers on how to safely stop antidepressants and manage withdrawal, which led me to co-found Outro Health."
Dr. Mark Horowitz
Co-Founder
Supporting a movement
We’re proud to support the various grassroots individuals and organizations, who have been advocating for deprescribing and informed consent for decades.
Built by world-leading experts in deprescribing
Drawing from clinical expertise and lived experience
Author of the Maudsley Deprescribing Guidelines. Lead Clinician at the NHS Deprescribing Clinic (UK).
Public health policy expert. Worked in health systems across five countries.
Assistant Professor of Psychiatry at UC Irvine. Published researcher on withdrawal and deprescribing.
Founder of Surviving Antidepressants and the Psychotropic Deprescribing Council.
Where is Outro Health’s program available?
Meet some of our dedicated clinicians
You don’t have to taper alone.
Start with a clinician-guided plan built around your medication, your symptoms, and your pace.
